In the recent years there has been both a significant technological development and an increase in the clinical implementation of CT Colonography (CTC). The history of CTC can be broken into three basic stages: that of technological development, which took place mainly in the 90s; the stage of clinical validation (approximately over the period 2003-2008), and the phase of diagnostic practice that is currently on-going. CTC is currently experiencing a rapid progression throughout Europe, from mainly academic reference centers that are principally involved in clinical validation, to other hospitals where CT colonography is now used as an alternative to the double-contrast barium enema.
