By Dr. Matthew J Kuhn, Dr. Julia W Patriarche & Dr. Miles A Kirchin
Gadolinium-based contrast agents (GBCAs) work by shortening the T1, T2, and T2* relaxation time constants of adjacent water protons in tissues. The greater the T1 shortening the greater the signal enhancement obtained on T1-weighted images.
Read More here: MRI macrocyclic contrast agents Kuhn Kirchin Patriarche DIEurope Spring 2022